July 23, 1965 - Grace Mugabe

Her ascent from secretary to First Lady tracked closely with her accumulation of influence, land, and wealth during one of Zimbabwe's most turbulent decades. Widely known by the nickname "Gucci Grace" for her extravagant spending during a period of hyperinflation and mass poverty, she was also implicated in violent incidents — most notably the assault of a model in South Africa — that drew international attention. As her husband's health declined, she positioned herself as a potential successor, reshaping ZANU-PF factions in ways that ultimately contributed to the conditions for the 2017 military intervention.

From Wikipedia

Grace Ntombizodwa Mugabe (formerly Goreraza, née Marufu; born 23 July 1965) is a Zimbabwean entrepreneur, politician and the widow of the late President Robert Mugabe. She served as the First Lady of Zimbabwe from 1996 until her husband's resignation in November 2017, a week after he was ousted from power in the 2017 Zimbabwean coup d'état.

Mugabe was cited as one of the Top 100 most influential Africans by New African magazine in 2014.